Sunday 23 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |   Krieschow vs FSV Mainz 05 | 0 - 9 | DFB Pokal Stage : Round of 64 | Sportpark Krieschow |
Saturday 29 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  FSV Mainz 05 vs SC Paderborn 07 | 0 - 0 | Bundesliga Stage : MD1 | Mewa Arena |
Sunday 6 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  Hamburger SV vs FSV Mainz 05 | 0 - 5 | Bundesliga Stage : MD2 | Volksparkstadion |
Saturday 12 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  FSV Mainz 05 vs Eintracht Frankfurt | - | Bundesliga Stage : MD3 | Mewa Arena |
Saturday 19 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  Borussia Mönchengladbach vs FSV Mainz 05 | - | Bundesliga Stage : MD4 | Borussia-Park |
Saturday 10 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  FSV Mainz 05 vs Bayer Leverkusen | - | Bundesliga Stage : MD5 | Mewa Arena |
Saturday 17 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  FC Schalke 04 vs FSV Mainz 05 | - | Bundesliga Stage : MD6 | Veltins Arena |
Saturday 24 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  FSV Mainz 05 vs Werder Bremen | - | Bundesliga Stage : MD7 | Mewa Arena |
Tuesday 27 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h00 |  VfL Bochum vs FSV Mainz 05 | - | DFB Pokal Stage : Round of 32 | Vonovia Ruhtadion |
Saturday 31 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  SV Elversberg vs FSV Mainz 05 | - | Bundesliga Stage : MD8 | Waldstadion Kaiserlinde |
Saturday 7 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  FSV Mainz 05 vs Bayern München | - | Bundesliga Stage : MD9 | Mewa Arena |
Saturday 21 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  FC Augsburg vs FSV Mainz 05 | - | Bundesliga Stage : MD10 | WWK Arena |
Saturday 28 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  FSV Mainz 05 vs Union Berlin | - | Bundesliga Stage : MD11 | Mewa Arena |
Saturday 5 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  RB Leipzig vs FSV Mainz 05 | - | Bundesliga Stage : MD12 | Red Bull Arena |
Saturday 12 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  FSV Mainz 05 vs SC Freiburg | - | Bundesliga Stage : MD13 | Mewa Arena |
Saturday 19 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  FSV Mainz 05 vs 1. FC Köln | - | Bundesliga Stage : MD14 | Mewa Arena |
Saturday 9 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  Borussia Dortmund vs FSV Mainz 05 | - | Bundesliga Stage : MD15 | Signal Iduna Park |
Tuesday 12 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h30 |  FSV Mainz 05 vs 1899 Hoffenheim | - | Bundesliga Stage : MD16 | Mewa Arena |
Saturday 16 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  VfB Stuttgart vs FSV Mainz 05 | - | Bundesliga Stage : MD17 | MHPArena |
Saturday 23 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | SC Paderborn 07 vs FSV Mainz 05 | - | Bundesliga Stage : MD18 | Home Deluxe Arena |
Saturday 30 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | FSV Mainz 05 vs Hamburger SV | - | Bundesliga Stage : MD19 | Mewa Arena |
Saturday 6 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | Eintracht Frankfurt vs FSV Mainz 05 | - | Bundesliga Stage : MD20 | Deutsche Bank Park |
Saturday 13 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | FSV Mainz 05 vs Borussia Mönchengladbach | - | Bundesliga Stage : MD21 | Mewa Arena |
Saturday 20 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | Bayer Leverkusen vs FSV Mainz 05 | - | Bundesliga Stage : MD22 | BayArena |
Saturday 27 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | FSV Mainz 05 vs FC Schalke 04 | - | Bundesliga Stage : MD23 | Mewa Arena |
Tuesday 2 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h30 | Werder Bremen vs FSV Mainz 05 | - | Bundesliga Stage : MD24 | Weserstadion |
Saturday 6 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | FSV Mainz 05 vs SV Elversberg | - | Bundesliga Stage : MD25 | Mewa Arena |
Saturday 13 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | Bayern München vs FSV Mainz 05 | - | Bundesliga Stage : MD26 | Allianz Arena |
Saturday 20 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | FSV Mainz 05 vs FC Augsburg | - | Bundesliga Stage : MD27 | Mewa Arena |
Saturday 3 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | Union Berlin vs FSV Mainz 05 | - | Bundesliga Stage : MD28 | - |
Saturday 10 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | FSV Mainz 05 vs RB Leipzig | - | Bundesliga Stage : MD29 | Mewa Arena |
Saturday 17 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | SC Freiburg vs FSV Mainz 05 | - | Bundesliga Stage : MD30 | Europa-Park Stadion |
Saturday 24 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | 1. FC Köln vs FSV Mainz 05 | - | Bundesliga Stage : MD31 | RheinEnergieStadion |
Saturday 8 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | FSV Mainz 05 vs Borussia Dortmund | - | Bundesliga Stage : MD32 | Mewa Arena |
Saturday 15 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | 1899 Hoffenheim vs FSV Mainz 05 | - | Bundesliga Stage : MD33 | PreZero Arena |
Saturday 22 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | FSV Mainz 05 vs VfB Stuttgart | - | Bundesliga Stage : MD34 | Mewa Arena |