Sunday 22 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 2h30 |   Houston Dynamo vs Chicago Fire | 2 - 1 | Major League Soccer Stage : MD1 | Shell Energy Stadium |
Sunday 1 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 2h30 |  Houston Dynamo vs Los Angeles FC | 0 - 2 | Major League Soccer Stage : MD2 | Shell Energy Stadium |
Sunday 15 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  Houston Dynamo vs Portland Timbers | 3 - 2 | Major League Soccer Stage : MD4 | Shell Energy Stadium |
Sunday 22 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  FC Dallas vs Houston Dynamo | 4 - 3 | Major League Soccer Stage : MD5 | Toyota Stadium |
Sunday 5 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  Houston Dynamo vs Seattle Sounders | 0 - 1 | Major League Soccer Stage : MD6 | Shell Energy Stadium |
Sunday 12 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 2h30 |  Colorado Rapids vs Houston Dynamo | 6 - 2 | Major League Soccer Stage : MD7 | Dick's Sporting Goods Park |
Sunday 19 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 0h30 |  Orlando City SC vs Houston Dynamo | 0 - 1 | Major League Soccer Stage : MD8 | Exploria Stadium |
Thursday 23 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  Houston Dynamo vs San Diego | 1 - 0 | Major League Soccer Stage : MD9 | Shell Energy Stadium |
Sunday 26 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  Austin vs Houston Dynamo | 2 - 0 | Major League Soccer Stage : MD10 | Q2 Stadium |
Sunday 3 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 | Houston Dynamo vs Colorado Rapids | 1 - 0 | Major League Soccer Stage : MD11 | Shell Energy Stadium |
Monday 11 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 2h00 | Los Angeles FC vs Houston Dynamo | 1 - 4 | Major League Soccer Stage : MD12 | BMO Stadium |
Thursday 14 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 2h30 |  Real Salt Lake vs Houston Dynamo | 3 - 0 | Major League Soccer Stage : MD13 | America First Field |
Sunday 17 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  Houston Dynamo vs Vancouver Whitecaps | 1 - 0 | Major League Soccer Stage : MD14 | Shell Energy Stadium |
Sunday 24 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 3h30 |  Los Angeles Galaxy vs Houston Dynamo | 1 - 1 | Major League Soccer Stage : MD15 | Dignity Health Sports Park |
Thursday 23 July
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  Houston Dynamo vs DC United | 1 - 1 | Major League Soccer Stage : MD16 | Shell Energy Stadium |
Sunday 26 July
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 | Houston Dynamo vs Austin | 3 - 0 | Major League Soccer Stage : MD17 | Shell Energy Stadium |
Sunday 2 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  Sporting Kansas City vs Houston Dynamo | 0 - 2 | Major League Soccer Stage : MD18 | Children's Mercy Park |
Saturday 8 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h30 |  New England Revolution vs Houston Dynamo | 0 - 2 | Major League Soccer Stage : MD3 | Gillette Stadium |
Sunday 16 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 | Houston Dynamo vs Los Angeles Galaxy | 1 - 0 | Major League Soccer Stage : MD19 | Shell Energy Stadium |
Thursday 20 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 3h30 | Vancouver Whitecaps vs Houston Dynamo | 0 - 1 | Major League Soccer Stage : MD20 | BC Place |
Sunday 23 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  St. Louis City vs Houston Dynamo | 2 - 1 | Major League Soccer Stage : MD21 | CITYPARK |
Sunday 30 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  Houston Dynamo vs San Jose Earthquakes | 0 - 0 | Major League Soccer Stage : MD22 | Shell Energy Stadium |
Sunday 6 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 0h30 |  Charlotte vs Houston Dynamo | 0 - 0 | Major League Soccer Stage : MD23 | Bank of America Stadium |
Thursday 10 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 | Houston Dynamo vs Real Salt Lake | 2 - 1 | Major League Soccer Stage : MD24 | Shell Energy Stadium |
Sunday 13 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 3h30 | San Jose Earthquakes vs Houston Dynamo | 1 - 0 | Major League Soccer Stage : MD25 | PayPal Park |
Sunday 20 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  Houston Dynamo vs FC Cincinnati | - | Major League Soccer Stage : MD26 | Shell Energy Stadium |
Sunday 27 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 | Houston Dynamo vs Sporting Kansas City | - | Major League Soccer Stage : MD27 | Shell Energy Stadium |
Sunday 11 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 |  Minnesota United FC vs Houston Dynamo | - | Major League Soccer Stage : MD28 | Allianz Field |
Thursday 15 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 3h30 | San Diego vs Houston Dynamo | - | Major League Soccer Stage : MD29 | Snapdragon Stadium |
Sunday 18 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 | Houston Dynamo vs FC Dallas | - | Major League Soccer Stage : MD30 | Shell Energy Stadium |
Sunday 25 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h30 | Houston Dynamo vs Minnesota United FC | - | Major League Soccer Stage : MD31 | Shell Energy Stadium |
Thursday 29 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 3h30 | Seattle Sounders vs Houston Dynamo | - | Major League Soccer Stage : MD32 | Lumen Field |
Monday 2 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 3h30 | Portland Timbers vs Houston Dynamo | - | Major League Soccer Stage : MD33 | Providence Park |
Sunday 8 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 1h00 | Houston Dynamo vs St. Louis City | - | Major League Soccer Stage : MD34 | Shell Energy Stadium |