Monday 17 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h15 |   Palermo vs Lecce | 2 - 0 | Coppa Italia Stage : Round of 64 | Stadio Renzo Barbera |
Sunday 23 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 |  Venezia vs Lecce | 0 - 2 | Serie A Stage : MD1 | Stadio Pierluigi Penzo |
Monday 31 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 |  Lecce vs AS Roma | 0 - 4 | Serie A Stage : MD2 | Via del Mare |
Monday 7 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 |  Cagliari vs Lecce | 1 - 0 | Serie A Stage : MD3 | Unipol Domus |
Sunday 13 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h00 |  Lecce vs Monza | 3 - 2 | Serie A Stage : MD4 | Via del Mare |
Sunday 20 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 19h45 |  AC Milan vs Lecce | - | Serie A Stage : MD5 | Stadio Giuseppe Meazza |
Sunday 11 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h00 |  Lecce vs Bologna | - | Serie A Stage : MD6 | Stadio Via del Mare |
Sunday 18 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 11h30 |  Udinese vs Lecce | - | Serie A Stage : MD7 | Bluenergy Stadium - Stadio Friuli |
Sunday 25 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h00 |  Lecce vs Juventus | - | Serie A Stage : MD8 | Stadio Via del Mare |
Thursday 29 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Frosinone vs Lecce | - | Serie A Stage : MD9 | Stadio Benito Stirpe |
Sunday 1 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h00 |  Lecce vs Genoa | - | Serie A Stage : MD10 | Stadio Via del Mare |
Saturday 7 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h00 |  Torino vs Lecce | - | Serie A Stage : MD11 | Stadio Olimpico di Torino |
Saturday 21 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h00 |  Lazio vs Lecce | - | Serie A Stage : MD12 | Stadio Olimpico |
Sunday 29 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Lecce vs Atalanta | - | Serie A Stage : MD13 | Stadio Via del Mare |
Sunday 6 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Napoli vs Lecce | - | Serie A Stage : MD14 | Stadio Diego Armando Maradona |
Sunday 13 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Lecce vs Sassuolo | - | Serie A Stage : MD15 | Stadio Via del Mare |
Sunday 20 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Lecce vs Inter | - | Serie A Stage : MD16 | Stadio Via del Mare |
Sunday 3 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Como vs Lecce | - | Serie A Stage : MD17 | Stadio Giuseppe Sinigaglia |
Wednesday 6 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Lecce vs Parma | - | Serie A Stage : MD18 | Stadio Via del Mare |
Sunday 10 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Fiorentina vs Lecce | - | Serie A Stage : MD19 | Stadio Artemio Franchi |
Sunday 17 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Lecce vs Udinese | - | Serie A Stage : MD20 | Stadio Via del Mare |
Sunday 24 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Lecce vs Torino | - | Serie A Stage : MD21 | Stadio Via del Mare |
Sunday 31 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Genoa vs Lecce | - | Serie A Stage : MD22 | Stadio Luigi Ferraris |
Sunday 7 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Lecce vs Napoli | - | Serie A Stage : MD23 | Stadio Via del Mare |
Sunday 14 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Monza vs Lecce | - | Serie A Stage : MD24 | - |
Sunday 21 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Lecce vs Frosinone | - | Serie A Stage : MD25 | Stadio Via del Mare |
Sunday 28 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Bologna vs Lecce | - | Serie A Stage : MD26 | Stadio Renato Dall'Ara |
Sunday 7 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Lecce vs Como | - | Serie A Stage : MD27 | Stadio Via del Mare |
Sunday 14 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Parma vs Lecce | - | Serie A Stage : MD28 | Stadio Ennio Tardini |
Sunday 21 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | AS Roma vs Lecce | - | Serie A Stage : MD29 | Stadio Olimpico |
Sunday 4 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Lecce vs Lazio | - | Serie A Stage : MD30 | Stadio Via del Mare |
Sunday 11 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Juventus vs Lecce | - | Serie A Stage : MD31 | Allianz Stadium |
Sunday 18 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Sassuolo vs Lecce | - | Serie A Stage : MD32 | - |
Sunday 25 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Lecce vs AC Milan | - | Serie A Stage : MD33 | Stadio Via del Mare |
Sunday 2 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Lecce vs Cagliari | - | Serie A Stage : MD34 | Stadio Via del Mare |
Sunday 9 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Inter vs Lecce | - | Serie A Stage : MD35 | - |
Sunday 16 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Lecce vs Fiorentina | - | Serie A Stage : MD36 | Stadio Via del Mare |
Sunday 23 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Atalanta vs Lecce | - | Serie A Stage : MD37 | New Balance Arena |
Sunday 30 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Lecce vs Venezia | - | Serie A Stage : MD38 | Stadio Via del Mare |