Saturday 22 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 12h30 |   Hull City vs Manchester United | 2 - 0 | Premier League Stage : MD1 | MKM Stadium |
Sunday 30 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h30 |  Manchester United vs Ipswich | 5 - 2 | Premier League Stage : MD2 | Old Trafford |
Sunday 6 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h00 |  Everton vs Manchester United | - | Premier League Stage : MD3 | Hill Dickinson Stadium |
Thursday 10 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h00 |  Manchester United vs Sabah FA | - | UEFA Champions League Stage : League phase J1 | Old Trafford |
Sunday 13 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h30 |  Manchester United vs Manchester City | - | Premier League Stage : MD4 | Old Trafford |
Sunday 20 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h30 |  Fulham vs Manchester United | - | Premier League Stage : MD5 | Craven Cottage |
Saturday 10 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 |  Manchester United vs Tottenham | - | Premier League Stage : MD6 | Old Trafford |
Tuesday 13 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h00 |  Atletico Madrid vs Manchester United | - | UEFA Champions League Stage : League phase J2 | Metropolitano Stadium |
Sunday 18 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h00 |  Leeds vs Manchester United | - | Premier League Stage : MD7 | Elland Road |
Wednesday 21 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h45 |  Como vs Manchester United | - | UEFA Champions League Stage : League phase J3 | - |
Sunday 25 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h00 |  Manchester United vs Bournemouth | - | Premier League Stage : MD8 | Old Trafford |
Saturday 31 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 13h30 |  Chelsea vs Manchester United | - | Premier League Stage : MD9 | Stamford Bridge |
Tuesday 3 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  Manchester United vs AS Roma | - | UEFA Champions League Stage : League phase J4 | Old Trafford |
Saturday 7 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 |  Manchester United vs Aston Villa | - | Premier League Stage : MD10 | Old Trafford |
Saturday 21 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 |  Liverpool vs Manchester United | - | Premier League Stage : MD11 | Anfield |
Wednesday 25 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  Sporting CP vs Manchester United | - | UEFA Champions League Stage : League phase J5 | - |
Saturday 28 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 |  Manchester United vs Brentford | - | Premier League Stage : MD12 | Old Trafford |
Wednesday 2 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  Newcastle vs Manchester United | - | Premier League Stage : MD13 | St. James' Park |
Saturday 5 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 |  Manchester United vs Coventry | - | Premier League Stage : MD14 | Old Trafford |
Tuesday 8 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  Manchester United vs RB Leipzig | - | UEFA Champions League Stage : League phase J6 | Old Trafford |
Saturday 12 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 |  Crystal Palace vs Manchester United | - | Premier League Stage : MD15 | Selhurst Park |
Saturday 19 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 |  Arsenal vs Manchester United | - | Premier League Stage : MD16 | Emirates Stadium |
Saturday 26 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 |  Manchester United vs Nottingham Forest | - | Premier League Stage : MD17 | Old Trafford |
Wednesday 30 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  Manchester United vs Sunderland | - | Premier League Stage : MD18 | Old Trafford |
Saturday 2 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 |  Brighton vs Manchester United | - | Premier League Stage : MD19 | Amex Stadium |
Wednesday 6 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 | Manchester United vs Newcastle | - | Premier League Stage : MD20 | Old Trafford |
Saturday 16 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 | Aston Villa vs Manchester United | - | Premier League Stage : MD21 | Villa Park |
Wednesday 20 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  Manchester United vs Bayern München | - | UEFA Champions League Stage : League phase J7 | Old Trafford |
Saturday 23 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 | Manchester United vs Liverpool | - | Premier League Stage : MD22 | Old Trafford |
Wednesday 27 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  Villarreal vs Manchester United | - | UEFA Champions League Stage : League phase J8 | de la Ceramica Stadium |
Saturday 30 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 | Brentford vs Manchester United | - | Premier League Stage : MD23 | Brentford Community Stadium |
Saturday 6 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 | Manchester United vs Chelsea | - | Premier League Stage : MD24 | Old Trafford |
Wednesday 10 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 | Manchester United vs Brighton | - | Premier League Stage : MD25 | Old Trafford |
Saturday 20 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 | Nottingham Forest vs Manchester United | - | Premier League Stage : MD26 | City Ground |
Saturday 27 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 | Manchester United vs Arsenal | - | Premier League Stage : MD27 | Old Trafford |
Wednesday 3 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 | Sunderland vs Manchester United | - | Premier League Stage : MD28 | Stadium of Light |
Saturday 13 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 | Manchester United vs Everton | - | Premier League Stage : MD29 | Old Trafford |
Saturday 20 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 | Manchester City vs Manchester United | - | Premier League Stage : MD30 | Etihad Stadium |
Saturday 10 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h00 | Manchester United vs Hull City | - | Premier League Stage : MD31 | Old Trafford |
Saturday 17 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h00 | Ipswich vs Manchester United | - | Premier League Stage : MD32 | Portman Road |
Saturday 24 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h00 | Manchester United vs Crystal Palace | - | Premier League Stage : MD33 | Old Trafford |
Saturday 1 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h00 | Coventry vs Manchester United | - | Premier League Stage : MD34 | Coventry Building Society Arena |
Saturday 8 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h00 | Bournemouth vs Manchester United | - | Premier League Stage : MD35 | Vitality Stadium |
Saturday 15 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h00 | Manchester United vs Leeds | - | Premier League Stage : MD36 | Old Trafford |
Sunday 23 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h00 | Tottenham vs Manchester United | - | Premier League Stage : MD37 | Tottenham Hotspur Stadium |
Sunday 30 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 16h00 | Manchester United vs Fulham | - | Premier League Stage : MD38 | Old Trafford |