Saturday 22 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h00 |   Eintracht Trier vs RB Leipzig | 0 - 6 | DFB Pokal Stage : Round of 64 | Moselstadion |
Saturday 29 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  RB Leipzig vs Borussia Mönchengladbach | 3 - 0 | Bundesliga Stage : MD1 | Red Bull Arena |
Saturday 5 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  Werder Bremen vs RB Leipzig | 3 - 1 | Bundesliga Stage : MD2 | Weserstadion |
Thursday 10 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h00 |  Como vs RB Leipzig | - | UEFA Champions League Stage : League phase Matchday 1 | Stadio Giuseppe Sinigaglia |
Sunday 13 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  RB Leipzig vs Hamburger SV | - | Bundesliga Stage : MD3 | Red Bull Arena |
Sunday 20 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  Bayer Leverkusen vs RB Leipzig | - | Bundesliga Stage : MD4 | BayArena |
Saturday 10 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  RB Leipzig vs Eintracht Frankfurt | - | Bundesliga Stage : MD5 | Red Bull Arena |
Tuesday 13 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h00 |  RB Leipzig vs PSV Eindhoven | - | UEFA Champions League Stage : League phase Matchday 2 | Red Bull Arena |
Saturday 17 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  Bayern München vs RB Leipzig | - | Bundesliga Stage : MD6 | Allianz Arena |
Wednesday 21 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h00 |  Real Madrid vs RB Leipzig | - | UEFA Champions League Stage : League phase Matchday 3 | - |
Saturday 24 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 |  RB Leipzig vs SV Elversberg | - | Bundesliga Stage : MD7 | Red Bull Arena |
Tuesday 27 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h00 |  Rot-Weiß Essen vs RB Leipzig | - | DFB Pokal Stage : Round of 32 | Stadion an der Hafenstrasse |
Saturday 31 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  FC Schalke 04 vs RB Leipzig | - | Bundesliga Stage : MD8 | Veltins Arena |
Wednesday 4 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  RB Leipzig vs Manchester City | - | UEFA Champions League Stage : League phase Matchday 4 | Red Bull Arena |
Saturday 7 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  RB Leipzig vs FC Augsburg | - | Bundesliga Stage : MD9 | Red Bull Arena |
Saturday 21 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  Union Berlin vs RB Leipzig | - | Bundesliga Stage : MD10 | - |
Tuesday 24 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  RB Leipzig vs Lens | - | UEFA Champions League Stage : League phase Matchday 5 | Red Bull Arena |
Saturday 28 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  SC Freiburg vs RB Leipzig | - | Bundesliga Stage : MD11 | Europa-Park Stadion |
Saturday 5 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  RB Leipzig vs FSV Mainz 05 | - | Bundesliga Stage : MD12 | Red Bull Arena |
Tuesday 8 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  Manchester United vs RB Leipzig | - | UEFA Champions League Stage : League phase Matchday 6 | Old Trafford |
Saturday 12 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  1. FC Köln vs RB Leipzig | - | Bundesliga Stage : MD13 | RheinEnergieStadion |
Saturday 19 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  RB Leipzig vs Borussia Dortmund | - | Bundesliga Stage : MD14 | Red Bull Arena |
Saturday 9 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  SC Paderborn 07 vs RB Leipzig | - | Bundesliga Stage : MD15 | Home Deluxe Arena |
Tuesday 12 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h30 |  RB Leipzig vs VfB Stuttgart | - | Bundesliga Stage : MD16 | Red Bull Arena |
Saturday 16 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 |  1899 Hoffenheim vs RB Leipzig | - | Bundesliga Stage : MD17 | PreZero Arena |
Wednesday 20 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  RB Leipzig vs Shakhtar Donetsk | - | UEFA Champions League Stage : League phase Matchday 7 | Red Bull Arena |
Saturday 23 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | Borussia Mönchengladbach vs RB Leipzig | - | Bundesliga Stage : MD18 | Borussia-Park |
Wednesday 27 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 21h00 |  Feyenoord vs RB Leipzig | - | UEFA Champions League Stage : League phase Matchday 8 | De Kuip |
Saturday 30 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | RB Leipzig vs Werder Bremen | - | Bundesliga Stage : MD19 | Red Bull Arena |
Saturday 6 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | Hamburger SV vs RB Leipzig | - | Bundesliga Stage : MD20 | Volksparkstadion |
Saturday 13 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | RB Leipzig vs Bayer Leverkusen | - | Bundesliga Stage : MD21 | Red Bull Arena |
Saturday 20 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | Eintracht Frankfurt vs RB Leipzig | - | Bundesliga Stage : MD22 | Deutsche Bank Park |
Saturday 27 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | RB Leipzig vs Bayern München | - | Bundesliga Stage : MD23 | Red Bull Arena |
Tuesday 2 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h30 | SV Elversberg vs RB Leipzig | - | Bundesliga Stage : MD24 | Waldstadion Kaiserlinde |
Saturday 6 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | RB Leipzig vs FC Schalke 04 | - | Bundesliga Stage : MD25 | Red Bull Arena |
Saturday 13 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | FC Augsburg vs RB Leipzig | - | Bundesliga Stage : MD26 | WWK Arena |
Saturday 20 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 15h30 | RB Leipzig vs Union Berlin | - | Bundesliga Stage : MD27 | Red Bull Arena |
Saturday 3 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | RB Leipzig vs SC Freiburg | - | Bundesliga Stage : MD28 | Red Bull Arena |
Saturday 10 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | FSV Mainz 05 vs RB Leipzig | - | Bundesliga Stage : MD29 | Mewa Arena |
Saturday 17 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | RB Leipzig vs 1. FC Köln | - | Bundesliga Stage : MD30 | Red Bull Arena |
Saturday 24 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | Borussia Dortmund vs RB Leipzig | - | Bundesliga Stage : MD31 | Signal Iduna Park |
Saturday 8 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | RB Leipzig vs SC Paderborn 07 | - | Bundesliga Stage : MD32 | Red Bull Arena |
Saturday 15 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | VfB Stuttgart vs RB Leipzig | - | Bundesliga Stage : MD33 | MHPArena |
Saturday 22 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h30 | RB Leipzig vs 1899 Hoffenheim | - | Bundesliga Stage : MD34 | Red Bull Arena |