Monday 17 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 |   Sassuolo vs Cesena | 3 - 0 | Coppa Italia Stage : Round of 64 | Mapei Stadium |
Sunday 23 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 19h45 |  Atalanta vs Sassuolo | 2 - 1 | Serie A Stage : MD1 | New Balance Arena |
Saturday 29 August
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 |  Sassuolo vs Torino | 2 - 1 | Serie A Stage : MD2 | Mapei Stadium |
Wednesday 2 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h00 |  Sassuolo vs Frosinone | 1 - 1 | Coppa Italia Stage : Round of 32 | Mapei Stadium |
Sunday 6 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h00 |  Bologna vs Sassuolo | 2 - 2 | Serie A Stage : MD3 | Renato Dall'Ara |
Sunday 13 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 19h45 |  Sassuolo vs Juventus | 3 - 2 | Serie A Stage : MD4 | Mapei Stadium |
Friday 18 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 19h45 |  Monza vs Sassuolo | 2 - 1 | Serie A Stage : MD5 | U-Power Stadium |
Sunday 11 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h00 |  Sassuolo vs AC Milan | 1 - 1 | Serie A Stage : MD6 | Mapei Stadium – Città del Tricolore |
Friday 16 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 19h45 | Frosinone vs Sassuolo | 4 - 2 | Serie A Stage : MD7 | PSC Arena |
Saturday 24 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 14h00 |  Como vs Sassuolo | - | Serie A Stage : MD8 | Stadio Giuseppe Sinigaglia |
Tuesday 27 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Sassuolo vs Lazio | - | Serie A Stage : MD9 | - |
Monday 2 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Sassuolo vs Fiorentina | - | Serie A Stage : MD10 | - |
Saturday 7 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h45 |  AS Roma vs Sassuolo | - | Serie A Stage : MD11 | Stadio Olimpico |
Sunday 22 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 12h30 |  Sassuolo vs Genoa | - | Serie A Stage : MD12 | - |
Sunday 29 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Sassuolo vs Napoli | - | Serie A Stage : MD13 | - |
Wednesday 2 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h00 | Juventus vs Sassuolo | - | Coppa Italia Stage : Round of 16 | Allianz Stadium |
Sunday 6 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Venezia vs Sassuolo | - | Serie A Stage : MD14 | Stadio Pierluigi Penzo |
Sunday 13 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Lecce vs Sassuolo | - | Serie A Stage : MD15 | Stadio Via del Mare |
Sunday 20 December
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Sassuolo vs Parma | - | Serie A Stage : MD16 | - |
Sunday 3 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Inter vs Sassuolo | - | Serie A Stage : MD17 | - |
Wednesday 6 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Sassuolo vs Udinese | - | Serie A Stage : MD18 | - |
Sunday 10 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 |  Cagliari vs Sassuolo | - | Serie A Stage : MD19 | Unipol Domus |
Sunday 17 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Sassuolo vs Monza | - | Serie A Stage : MD20 | - |
Sunday 24 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Fiorentina vs Sassuolo | - | Serie A Stage : MD21 | Stadio Artemio Franchi |
Sunday 31 January
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Sassuolo vs Como | - | Serie A Stage : MD22 | - |
Sunday 7 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Juventus vs Sassuolo | - | Serie A Stage : MD23 | Allianz Stadium |
Sunday 14 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Torino vs Sassuolo | - | Serie A Stage : MD24 | Stadio Olimpico di Torino |
Sunday 21 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Sassuolo vs AS Roma | - | Serie A Stage : MD25 | - |
Sunday 28 February
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Parma vs Sassuolo | - | Serie A Stage : MD26 | Stadio Ennio Tardini |
Sunday 7 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Sassuolo vs Bologna | - | Serie A Stage : MD27 | - |
Sunday 14 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | AC Milan vs Sassuolo | - | Serie A Stage : MD28 | Stadio Giuseppe Meazza |
Sunday 21 March
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 18h30 | Sassuolo vs Cagliari | - | Serie A Stage : MD29 | - |
Sunday 4 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Sassuolo vs Atalanta | - | Serie A Stage : MD30 | - |
Sunday 11 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Napoli vs Sassuolo | - | Serie A Stage : MD31 | Stadio Diego Armando Maradona |
Sunday 18 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Sassuolo vs Lecce | - | Serie A Stage : MD32 | - |
Sunday 25 April
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Genoa vs Sassuolo | - | Serie A Stage : MD33 | Stadio Luigi Ferraris |
Sunday 2 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Sassuolo vs Frosinone | - | Serie A Stage : MD34 | - |
Sunday 9 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Lazio vs Sassuolo | - | Serie A Stage : MD35 | Stadio Olimpico |
Sunday 16 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Sassuolo vs Venezia | - | Serie A Stage : MD36 | - |
Sunday 23 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Udinese vs Sassuolo | - | Serie A Stage : MD37 | Bluenergy Stadium - Stadio Friuli |
Sunday 30 May
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 17h30 | Sassuolo vs Inter | - | Serie A Stage : MD38 | - |
