Tuesday 8 September
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 19h00 |   Exeter City vs Tottenham Hotspur U21 | - | EFL Trophy Group South Stage : MD1 | St James Park |
Tuesday 13 October
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 19h00 |  Cheltenham vs Tottenham Hotspur U21 | - | EFL Trophy Group South Stage : MD1 | Whaddon Road |
Tuesday 24 November
| Time | Match | Score | Competition | Stadium |
|---|---|---|---|---|
| 20h00 |  Oxford United vs Tottenham Hotspur U21 | - | EFL Trophy Group South Stage : MD1 | Kassam Stadium |