Sunday 22 February
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 4h30 |   Portland Timbers vs Columbus Crew | 3 - 2 | Major League Soccer Phase : J1 | Providence Park |
Sunday 1 March
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 2h30 |  Sporting Kansas City vs Columbus Crew | 2 - 2 | Major League Soccer Phase : J2 | Children's Mercy Park |
Sunday 8 March
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 1h30 |  Columbus Crew vs Chicago Fire | 0 - 0 | Major League Soccer Phase : J3 | ScottsMiracle-Gro Field |
Saturday 14 March
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 23h15 |  Columbus Crew vs Nashville SC | 0 - 1 | Major League Soccer Phase : J4 | Lower.com Field |
Saturday 21 March
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 18h00 |  Toronto FC vs Columbus Crew | 2 - 1 | Major League Soccer Phase : J5 | BMO Field |
Sunday 5 April
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  Atlanta United FC vs Columbus Crew | 1 - 3 | Major League Soccer Phase : J6 | Stade Mercedes-Benz |
Monday 13 April
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h00 |  Columbus Crew vs Orlando City SC | 1 - 1 | Major League Soccer Phase : J7 | Lower.com Field |
Sunday 19 April
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  New England Revolution vs Columbus Crew | 2 - 1 | Major League Soccer Phase : J8 | Stade Gillette |
Thursday 23 April
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  Columbus Crew vs Los Angeles Galaxy | 2 - 1 | Major League Soccer Phase : J9 | Lower.com Field |
Sunday 26 April
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  Columbus Crew vs Philadelphia Union | 2 - 0 | Major League Soccer Phase : J10 | Lower.com Field |
Sunday 3 May
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  Columbus Crew vs Minnesota United FC | 2 - 3 | Major League Soccer Phase : J11 | Lower.com Field |
Sunday 10 May
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 21h30 |  New York City FC vs Columbus Crew | 3 - 0 | Major League Soccer Phase : J12 | Stade Yankee |
Thursday 14 May
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  New York Red Bulls vs Columbus Crew | 3 - 2 | Major League Soccer Phase : J13 | Stade Sports Illustrated |
Sunday 17 May
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 | Philadelphia Union vs Columbus Crew | 1 - 1 | Major League Soccer Phase : J14 | Subaru Park |
Sunday 24 May
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 22h00 | Columbus Crew vs Atlanta United FC | 2 - 0 | Major League Soccer Phase : J15 | Lower.com Field |
Thursday 23 July
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 | Columbus Crew vs New York City FC | 1 - 2 | Major League Soccer Phase : J16 | Lower.com Field |
Sunday 26 July
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h15 |  Columbus Crew vs FC Cincinnati | 2 - 1 | Major League Soccer Phase : J17 | Lower.com Field |
Sunday 2 August
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  Inter Miami vs Columbus Crew | 2 - 2 | Major League Soccer Phase : J18 | Stade Nu |
Sunday 16 August
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  Charlotte vs Columbus Crew | 3 - 1 | Major League Soccer Phase : J19 | Stade Bank of America |
Thursday 20 August
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  Columbus Crew vs CF Montreal | 1 - 2 | Major League Soccer Phase : J20 | Lower.com Field |
Sunday 23 August
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 1h30 | Nashville SC vs Columbus Crew | 3 - 2 | Major League Soccer Phase : J21 | Geodis Park |
Sunday 30 August
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 21h30 | Columbus Crew vs New England Revolution | 1 - 3 | Major League Soccer Phase : J22 | Lower.com Field |
Sunday 6 September
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  Columbus Crew vs Colorado Rapids | 3 - 0 | Major League Soccer Phase : J23 | Lower.com Field |
Thursday 10 September
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 |  DC United vs Columbus Crew | 2 - 1 | Major League Soccer Phase : J24 | Audi Field |
Sunday 13 September
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 | Columbus Crew vs New York Red Bulls | 0 - 1 | Major League Soccer Phase : J25 | ScottsMiracle-Gro Field |
Sunday 20 September
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 | CF Montreal vs Columbus Crew | - | Major League Soccer Phase : J26 | Stade Saputo |
Monday 28 September
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h00 | Columbus Crew vs Inter Miami | - | Major League Soccer Phase : J27 | ScottsMiracle-Gro Field |
Sunday 11 October
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 | Orlando City SC vs Columbus Crew | - | Major League Soccer Phase : J28 | Stade Exploria |
Thursday 15 October
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h30 | Columbus Crew vs Charlotte | - | Major League Soccer Phase : J29 | ScottsMiracle-Gro Field |
Monday 19 October
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 0h00 | FC Cincinnati vs Columbus Crew | - | Major League Soccer Phase : J30 | Stade TQL |
Saturday 24 October
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 20h30 | Columbus Crew vs Toronto FC | - | Major League Soccer Phase : J31 | ScottsMiracle-Gro Field |
Thursday 29 October
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 1h30 |  FC Dallas vs Columbus Crew | - | Major League Soccer Phase : J32 | Stade Toyota |
Saturday 31 October
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 19h00 | Columbus Crew vs DC United | - | Major League Soccer Phase : J33 | ScottsMiracle-Gro Field |
Saturday 7 November
| Heure | Match | Score | Compétition | Stade |
|---|---|---|---|---|
| 22h00 | Chicago Fire vs Columbus Crew | - | Major League Soccer Phase : J34 | Soldier Field |